Jacqueline Karlin

About Jacqueline

Jacqueline Karlin is the founder of the Agentic Commerce Advisory, a boutique practice helping commerce leaders build for the agent economy. Most recently, she was Senior Director of AI Products at PayPal, where she led the company's entry into the agentic commerce ecosystem. Her team built the framework for PayPal to be invoked by agents — including early adoption of MCP servers and agent-to-agent protocols — alongside AI-driven personalization that anticipates customer demand. The work spanned the full consumer journey, from discovery to payment. Earlier roles include Meta/WhatsApp (Director of Operations, leading risk, payments, and conversational commerce), Expedia (Senior Director of E-commerce Suite, with prior responsibility for payments), and Amazon, where she ran international expansion of Alexa Voice Services across eight countries and developed Amazon Lending products providing working capital to marketplace sellers. Across each, the work followed a consistent pattern: 0-to-1 product cycles at the intersection of AI and commerce, translating early technical vision into platforms that drive real revenue at global scale. Jacqueline holds an MBA from MIT. She founded Agentic Commerce Advisory in 2026 to bring that operating experience to a small number of commerce leaders. Her view is that to actually compete in agentic commerce, leaders will need to redesign their commercial stack and rethink revenue streams. The pivotal shifts are already underway: discovery is moving from search-engine results to agent recommendations, transactions are moving from checkout pages to authenticated agent calls, and the unit economics of commerce are being rewritten as compute costs collide with conversion. Most commerce leaders see the shift coming. Few have the operating playbook to navigate it. The practice exists to close that gap.

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